Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060794 | 1.00 | EPHX2 (0.43) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9060788 | 1.00 | EPHX2 (0.43) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL7525050 | 0.96 | EPHX2 (0.42) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8094823 | 0.96 | EPHX2 (0.42) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL7525054 | 0.96 | EPHX2 (0.42) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9061735 | 0.96 | HTT (0.45) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9061739 | 0.96 | HTT (0.45) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9061291 | 0.95 | EPHX2 (0.42) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9061300 | 0.95 | EPHX2 (0.42) | EPHX2POLBHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9062009 | 0.95 | EPHX2 (0.42) | EPHX2POLBHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5324449-A | Substituted phenyl trifluoromethyl ethers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-28 | — | — | US | disclosed |