Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194346 | 0.95 | CHRM2 (0.62) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL9385011 | 0.94 | TSHR (0.64) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL259753 | 0.90 | TSHR (0.68) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL9450937 | 0.87 | TSHR (0.64) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL5093330 | 0.85 | CHRM2 (0.61) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL18067961 | 0.85 | CHRM2 (0.60) | TSHRCHRM2KCNH2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5099421 | 0.84 | CHRM2 (0.59) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL8780911 | 0.84 | CHRM2 (0.59) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL3118575 | 0.84 | CHRM2 (0.59) | TSHRCHRM2KCNH2MEN1KMT2A | |
| SCHEMBL378397 | 0.83 | TSHR (0.78) | TSHRCHRM2KCNH2KCNJ1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3112948-A | — | — | None | — | — | JP | disclosed |
| JP-8157429-A | — | — | None | — | — | JP | disclosed |
| CN-105777559-A | Synthesis method of nifekalant hydrochloride medical intermediate 2-[3-(4-nitrophenyl) propyl amino] ethyl alcohol | 成都千叶龙华石油工程技术咨询有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105777559-A | Synthesis method of nifekalant hydrochloride medical intermediate 2-[3-(4-nitrophenyl) propyl amino] ethyl alcohol | 成都千叶龙华石油工程技术咨询有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-103288751-B | A kind of preparation method of high-purity nifekalant hydrochloride | BAILI PHARMACEUTICAL CO., LTD., SICHUAN PROV. (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-103288751-A | Preparation method of high-purity nifekalant hydrochloride | SICHUAN BIOKIN PHARMACEUTICAL CO LTD | 2013-09-11 | — | — | CN | disclosed |
| JP-H08157429-A | PRODUCTION OF N-(2-HYDROXYETHYL)-3-(4-NITROPHENYL) PROPYLAMINE | MITSUI TOATSU CHEM INC | 1996-06-18 | — | — | JP | disclosed |
| EP-0478268-B1 | Polymerizable substituted amide compound, polymer obtained therefrom and nonlinear optical material using the same | NIPPON PAINT CO LTD (JP) | 1995-11-15 | — | — | EP | disclosed |
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5274061-A | A 4-nitophenylaminoimido pendant group oriented by an electric field | NIPPON PAINT CO., LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5200552-A | POLYMERIZABLE SUBSTITUTED AMIDE COMPOUND, POLYMER OBTAINED THEREFROM AND NONLINEAR OPTICAL MATERIAL USING THE SAME | NIPPON PAINT CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0478268-A1 | Polymerizable substituted amide compound, polymer obtained therefrom and nonlinear optical material using the same | Nippon Paint Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |
| JP-H03112948-A | N-(2-HYDROXYETHYL)-3-(4-NITROPHENYL)PROPYLAMINE AND PRODUCTION THEREOF | MITSUI TOATSU CHEM INC | 1991-05-14 | — | — | JP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |