SCHEMBL9060955

SCHEMBL9060955

CCCCCCCCOc1ccc(-c2ccc(Br)cc2F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.49
PTPN11 Q06124 2/20 0.47
NR5A1 Q13285 1/20 0.46
RARB P10826 5/20 0.46
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
LTA4H P09960 1/20 0.42
RARA P10276 1/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
PLA2G4B P0C869 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9226935 1.00 MAPT (0.49) MAPTPTPN11NR5A1RARBTP53
SCHEMBL9222729 1.00 MAPT (0.49) MAPTPTPN11NR5A1RARBTP53
SCHEMBL10693987 0.96 CYP2D6 (0.45) MAPTPTPN11RARBCYP3A4CYP2D6
SCHEMBL9845134 0.92 PTPN11 (0.50) MAPTPTPN11NR5A1RARBTSHR
SCHEMBL9247693 0.88 PTPN11 (0.54) PTPN11NR5A1RARBTP53TSHR
SCHEMBL9244788 0.88 PTPN11 (0.54) PTPN11NR5A1RARBTP53TSHR
SCHEMBL9223360 0.86 PTPN11 (0.49) PTPN11NR5A1RARBTP53TSHR
SCHEMBL9228239 0.86 PTPN11 (0.49) PTPN11NR5A1RARBTP53TSHR
SCHEMBL9219095 0.86 PTPN11 (0.49) PTPN11NR5A1RARBTP53TSHR
SCHEMBL9219108 0.86 PTPN11 (0.49) PTPN11NR5A1RARBTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5494605-A FERROELECTRIC, CHEMICALLY STABLE WITH WIDE TEMPERATURE RANGE KANTO KAGAKU KABUSHIKI KAISHA (JP) 1996-02-27 US disclosed
US-5382380-A Ferroelectric material for displays KANTO KAGAKU KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed
EP-0414230-B1 Liquid crystal composition and liquid crystal device containing the same SHARP KK (JP) 1995-01-04 EP disclosed
EP-0360043-B1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU (JP) 1994-11-09 EP disclosed
US-5271867-A Liquid crystal composition and liquid crystal device containing the same SHARP KABUSHIKI KAISHA (JP) 1993-12-21 US disclosed
EP-0360042-B1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU (JP) 1993-11-03 EP disclosed
EP-0414230-A2 Liquid crystal composition and liquid crystal device containing the same SHARP KABUSHIKI KAISHA (JP) 1991-02-27 EP disclosed
EP-0360043-A1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0360042-A1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed