SCHEMBL9061306

SCHEMBL9061306

CCCCCCCCCC1CCC(c2ccc(OC(F)F)cc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.43
SPHK1 Q9NYA1 10/20 0.42
CYP2C9 P11712 1/20 0.41
MAPT P10636 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.39
SPHK2 Q9NRA0 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4800745 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9061297 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9061045 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9061690 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9061703 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9061050 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9061784 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9060167 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL9061780 1.00 IDO1 (0.43) IDO1SPHK1CYP2C9MAPTALDH1A1
SCHEMBL4800577 0.99 IDO1 (0.44) IDO1SPHK1CYP2C9MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5536442-A ELECTROOPTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-07-16 US disclosed
US-5389292-A Liquid crystalline media having positive dielctric anisotropy, chemical, heat and radiation resistance, used as electro-optical displaying MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-14 US disclosed