⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Charcoal, Activated SCHEMBL135103 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL10382275 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL912261 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL546900 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL29735756 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL55999 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL912751 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL30477715 | 0.50 | — | — | |
| Charcoal, Activated SCHEMBL7749920 | 0.41 | — | — | |
| Charcoal, Activated SCHEMBL7865461 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169286-B2 | Use of N-alkyl imidazole for sulfurization of oligonucleotides with an acetyl disulfide | AGILENT TECHNOLOGIES, INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-8642755-B2 | Use of thioacetic acid derivatives in the sulfurization of oligonucleotides with phenylacetyl disulfide | AGILENT TECHNOLOGIES, INC. (US) | 2014-02-04 | — | — | US | disclosed |
| US-20130035261-A1 | USE OF N-ALKYL IMIDAZOLE FOR SULFURIZATION OF OLIGONUCLEOTIDES WITH AN ACETYL DISULFIDE | AGILENT TECHNOLOGIES, INC. (US) | 2013-02-07 | — | — | US | disclosed |
| US-8309710-B2 | Use of N-alkyl imidazole for sulfurization of oligonucleotides with an acetyl disulfide | AGILENT TECHNOLOGIES, INC. (US) | 2012-11-13 | — | — | US | disclosed |
| EP-2277886-B1 | The use of n-alkyl imidazole for sulfurization of oligonucleotides with an acetyl disulfide | AGILENT TECHNOLOGIES INC (US) | 2012-10-24 | — | — | EP | disclosed |
| EP-2277886-A1 | The use of n-alkyl imidazole for sulfurization of oligonucleotides with an acetyl disulfide | Agilent Technologies, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| US-20100331532-A1 | Use Of N-Alkyl Imidazole For Sulfurization Of Oligonucleotides With An Acetyl Disulfide | AGILENT TECHNOLOGIES, INC. | 2010-12-30 | — | — | US | disclosed |
| US-20100331533-A1 | Use Of Thioacetic Acid Derivatives In The Sulfurization Of Oligonucleotides With Phenylacetyl Disulfide | AGILENT TECHNOLOGIES, INC. | 2010-12-30 | — | — | US | disclosed |