SCHEMBL9062140

SCHEMBL9062140

CCOC(=O)C(=Cc1ccc(OCCOC(=O)Cl)cc1)C(=O)OCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.61
KMT2A Q03164 9/20 0.57
MEN1 O00255 8/20 0.57
MAPT P10636 8/20 0.57
LMNA P02545 4/20 0.57
NPSR1 Q6W5P4 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
S1PR4 O95977 1/20 0.57
S1PR1 P21453 1/20 0.57
MAPK1 P28482 1/20 0.57
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 4/20 0.48
HSP90AA1 P07900 3/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.46
MITF O75030 1/20 0.46
HTT P42858 1/20 0.46
PLIN1 O60240 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9061094 0.88 NR1H4 (0.46) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL11330304 0.86 NR1H4 (0.67) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL13766391 0.84 NR1H4 (0.58) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL11100803 0.84 NR1H4 (0.72) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL9473881 0.83 NR1H4 (0.64) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL12869943 0.83 NR1H4 (0.70) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL8332854 0.82 NR1H4 (0.62) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL3687136 0.82 NR1H4 (0.62) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL1068265 0.81 MEN1 (0.85) NR1H4KMT2AMEN1MAPTLMNA
SCHEMBL8393508 0.80 NR1H4 (0.60) NR1H4KMT2AMEN1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472819-B1 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ATOCHEM NORTH AMERICA ELF (US) 1996-08-21 EP disclosed
US-5457162-A Catalyst for addition polymerization, curing and crosslinking ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-10-10 US disclosed
US-5399630-A Process for curing polymers using amino or hydrazino peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-03-21 US disclosed
EP-0355733-B1 Amino or hydrazino peroxides, derivatives and their uses ATOCHEM NORTH AMERICA (US) 1995-02-08 EP disclosed
US-5360867-A Reactive with maleic acid or maleic anhydride polymer ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-11-01 US disclosed
US-5272219-A Process for preparing amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-12-21 US disclosed
EP-0472819-A2 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-04 EP disclosed
US-5039754-A Block copolymer;compatibilizing polymer blends and alloy ATOCHEM NORTH AMERICA, INC. (US) 1991-08-13 US disclosed
US-4956416-A CURING UNSATURATED POLYESTERS; ADDITION POLYMERIZATION CATALYSTS; COAVALENTLY BOUND PERFORMANCE ADDITIVE FUNCTIONS; GRAFT AND BLOCK POLYMERS; SELF-CURING ATOCHEM NORTH AMERICA, INC. (US) 1990-09-11 US disclosed
EP-0355733-A1 Amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-02-28 EP disclosed