SCHEMBL9062200

SCHEMBL9062200

O=C(O)c1ccc(C(=O)c2ccc3c(c2)C(=O)OC3=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 8/20 0.54
CA12 O43570 5/20 0.52
CA7 P43166 5/20 0.52
CA1 P00915 4/20 0.52
CA4 P22748 2/20 0.52
CYP2C8 P10632 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
ENPP2 Q13822 1/20 0.49
TTR P02766 1/20 0.49
PTPRC P08575 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27356295 0.93 CA12 (0.50) SRD5A2CA12CA7CA1CA4
SCHEMBL1271059 0.91 TDP1 (0.55) SRD5A2CA12CA7CA1CA4
SCHEMBL7822013 0.91 SRD5A2 (0.61) SRD5A2CA12CA7CA1CA4
SCHEMBL169521 0.91 CA12 (0.51) CA12CA7CA1CA4ALDH1A1
SCHEMBL9328144 0.90 CA12 (0.50) SRD5A2CA12CA7CA1CA4
SCHEMBL22458 0.89 TTR (0.60) CA12CA7CA1CA4ALDH1A1
SCHEMBL1080970 0.89 TTR (0.60) CA12CA7CA1CA4ALDH1A1
SCHEMBL29355829 0.89 TTR (0.60) CA12CA7CA1CA4ALDH1A1
Benzoic Acid SCHEMBL27945375 0.87 TTR (0.59) SRD5A2CA12CA7CA1CA4
Bromide SCHEMBL8174305 0.87 TTR (0.58) CA12CA7CA1CA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8325201-A None JP disclosed
JP-H08325201-A PRODUCTION OF ALICYCLIC POLYCARBOXYLIC ACID ESTER NEW JAPAN CHEM CO LTD 1996-12-10 JP disclosed
US-5576398-A POLYCARBODIIMIDES GRAFTED WITH CARBOXYLIC ANHYDRIDE AND EPOXY COMPOUND FOR MOLDING MATERIALS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-11-19 US disclosed