⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667670 | 0.86 | — | — | |
| SCHEMBL9119251 | 0.83 | — | — | |
| SCHEMBL6654204 | 0.81 | — | — | |
| SCHEMBL28789940 | 0.78 | — | — | |
| SCHEMBL18362217 | 0.74 | — | — | |
| SCHEMBL18362197 | 0.74 | — | — | |
| SCHEMBL584203 | 0.74 | — | — | |
| SCHEMBL20548212 | 0.74 | — | — | |
| SCHEMBL9558869 | 0.74 | — | — | |
| SCHEMBL14127424 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292439-A | Flow through regenerated ion exchange resin containing copolymer of a poly- and and mono-vinyl compound as matrix | MITSUBISHI KASEI CORPORATION (JP) | 1994-03-08 | — | — | US | claimed |
| EP-4691465-A2 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | The Trustees of Columbia University in the City of New York (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4036094-B1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | UNIV COLUMBIA (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250320218-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-10-16 | — | — | US | disclosed |
| US-12404277-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-09-02 | — | — | US | disclosed |
| US-20230312585-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-10-05 | — | — | US | disclosed |
| US-11649240-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-05-16 | — | — | US | disclosed |
| CN-111393434-B | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2022-11-04 | — | — | CN | disclosed |
| EP-4036094-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | The Trustees of Columbia University in the City of New York (US) | 2022-08-03 | — | — | EP | disclosed |
| EP-3137168-B1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | UNIV COLUMBIA (US) | 2022-01-05 | — | — | EP | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| CN-1100728-A | Nucleosides and oligonucleotides having 2'-ether groups | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | CN | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
| US-5292439-A | Flow through regenerated ion exchange resin containing copolymer of a poly- and and mono-vinyl compound as matrix | MITSUBISHI KASEI CORPORATION (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5055581-A | Dehydrochlorination reaction between n-alkyl substituted piperazine and bis(-chloroalkyl) ether; useful for urethane forming reaction | SAN-APRO LIMITED (JP) | 1991-10-08 | — | — | US | disclosed |
| US-4771047-A | VASODILATION, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-09-13 | — | — | US | disclosed |
| US-4330376-A | RHODIUM COATING | ATLANTIC RICHFIELD COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4238551-A | RHODIUM COATING, ACID RESISTANCE | HALCON RESEARCH & DEVELOPMENT CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |
| US-4153806-A | Recovery of vicinal glycol esters by plural stage distillation | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1979-05-08 | — | — | US | disclosed |