⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL28063960 | 0.90 | TSHR (0.32) | — | |
| Propene SCHEMBL11255860 | 0.85 | — | — | |
| SCHEMBL10965091 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL27933 | 0.74 | — | — | |
| SCHEMBL23581065 | 0.74 | — | — | |
| SCHEMBL29039520 | 0.72 | — | — | |
| SCHEMBL1074130 | 0.72 | — | — | |
| SCHEMBL11599464 | 0.69 | — | — | |
| SCHEMBL20456069 | 0.68 | MEN1 (0.32) | — | |
| SCHEMBL6593385 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103408441-A | Synthetic method of bi(2-methoxyl ethyl)amine | ANQING FENGYUAN CHEMICAL CO LTD | 2013-11-27 | — | — | CN | claimed |
| CN-103265456-A | Preparation method of intermediate of medicament erlotinib for lung cancer targeted therapy | HUANGSHAN SHEXIAN HONGHUI CHEMICAL CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-101671238-B | Preparation method of 2-bromoethyl methyl ether | YANGZHOU PRINCECHEM CO LTD | 2012-07-04 | — | — | CN | claimed |
| CN-121949432-A | Cysteine specific coupling nucleophile and preparation method and application thereof | 河南师范大学 | 2026-05-01 | — | — | CN | disclosed |
| EP-4691465-A2 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | The Trustees of Columbia University in the City of New York (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4036094-B1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | UNIV COLUMBIA (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250320218-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-10-16 | — | — | US | disclosed |
| US-12404277-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-09-02 | — | — | US | disclosed |
| US-20230312585-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-10-05 | — | — | US | disclosed |
| US-11649240-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-05-16 | — | — | US | disclosed |
| CN-111393434-B | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2022-11-04 | — | — | CN | disclosed |
| CN-1100728-A | Nucleosides and oligonucleotides having 2'-ether groups | CIBA GEIGY AG (CH) | 1995-03-29 | — | — | CN | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |
| CN-1094727-A | The 5-(hetero) aryl indole derivatives | PFIZER (US) | 1994-11-09 | — | — | CN | disclosed |
| CN-1083059-A | The indoles that 3-piperidine methyl carboxylicesters replaces | GLAXO GROUP LTD (GB) | 1994-03-02 | — | — | CN | disclosed |
| CN-1050023-A | The method for preparing cephalosporin derivative | BEECHAM GROUP PLC (GB) | 1991-03-20 | — | — | CN | disclosed |
| US-4771047-A | VASODILATION, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-09-13 | — | — | US | disclosed |
| US-4330376-A | RHODIUM COATING | ATLANTIC RICHFIELD COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4321231-A | IN TH PRESENCE OF AN ACID, USING A TELLURIUM OR SELENIUM COMPOUND | ATLANTIC RICHFIELD COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| US-4238551-A | RHODIUM COATING, ACID RESISTANCE | HALCON RESEARCH & DEVELOPMENT CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |