Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545075 | 0.85 | CRBN (0.36) | CRBNTSHR | |
| SCHEMBL2541924 | 0.85 | CRBN (0.36) | CRBNTSHR | |
| SCHEMBL21344935 | 0.84 | — | — | |
| SCHEMBL23867157 | 0.79 | CRBN (0.32) | CRBNTSHR | |
| SCHEMBL21649516 | 0.79 | CRBN (0.32) | CRBNTSHR | |
| SCHEMBL12653639 | 0.72 | — | — | |
| SCHEMBL2548118 | 0.70 | CRBN (0.36) | CRBNTSHR | |
| SCHEMBL12653612 | 0.70 | CRBN (0.36) | CRBNTSHR | |
| SCHEMBL2548921 | 0.70 | CRBN (0.36) | CRBNTSHR | |
| SCHEMBL8717472 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299421-B1 | Imide modified epoxy resins | DOW CHEMICAL CO (US) | 1996-03-13 | — | — | EP | claimed |
| US-4847348-A | BINDERS, COATINGS | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | claimed |
| EP-0299421-A2 | Imide modified epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1989-01-18 | — | — | EP | claimed |
| US-9181277-B2 | Aminoquinazoline derivatives and their salts and methods of use | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-10 | — | — | US | disclosed |
| US-20140228361-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228361-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE | ABL1, PRKDC, JAK2 | CRBN 1741/4885PARP1 1291/4885TSHR 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.