Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063066 | 1.00 | POLB (0.53) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL9063056 | 1.00 | POLB (0.53) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL9062757 | 0.96 | POLB (0.53) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL9063071 | 0.96 | POLB (0.53) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL9062750 | 0.96 | POLB (0.53) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL8945838 | 0.94 | HSP90AA1 (0.55) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL8590568 | 0.94 | HSP90AA1 (0.55) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL7157837 | 0.94 | HSP90AA1 (0.55) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL9305133 | 0.94 | HSP90AA1 (0.55) | POLBPOLA1HSP90AA1FAAHDGKA | |
| SCHEMBL8423003 | 0.94 | HSP90AA1 (0.55) | POLBPOLA1HSP90AA1FAAHDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652862-B1 | AMIDOACIDS BY ALKALI HYDROLYSIS OF AMIDOESTERS | AKZO NOBEL NV (NL) | 1996-10-30 | — | — | EP | disclosed |
| EP-0652862-A1 | AMIDOACIDS BY ALKALI HYDROLYSIS OF AMIDOESTERS. | AKZO NOBEL NV (NL) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994003422-A1 | AMIDOACIDS BY ALKALI HYDROLYSIS OF AMIDOESTERS | AKZO NOBEL N.V. (NL) | 1994-02-17 | — | — | WO | disclosed |