SCHEMBL9063752

SCHEMBL9063752

O=C(O)c1nonc1C(O)=S

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
STAT5B P51692 1/20 0.33
KMT2A Q03164 1/20 0.31
PTPN1 P18031 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482891 0.87 STAT5B (0.38) STAT5BKMT2APTPN1ALDH1A1MAPT
SCHEMBL1043406 0.72
SCHEMBL30999036 0.71 STAT5B (0.35) STAT5BKMT2A
SCHEMBL1001730 0.70
SCHEMBL261709 0.70
SCHEMBL23989946 0.65 KMT2A (0.33) STAT5BKMT2AALDH1A1SMN1; SMN2
SCHEMBL22207617 0.65 GRIA1 (0.32) STAT5BALDH1A1
SCHEMBL21616807 0.65 STAT5B (0.37) STAT5BKMT2AALDH1A1SMN1; SMN2
SCHEMBL22207677 0.65 IKBKE (0.35) STAT5B
SCHEMBL23991225 0.65 CA1 (0.42) STAT5BALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4123424-A Polymeric piperazinamides and membranes for reverse osmosis made therefrom MONTEDISON S.P.A. (IT) 1978-10-31 US claimed
EP-0510545-B1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM SPA (IT) 1996-10-02 EP disclosed
EP-0435346-B1 Elastomeric thermoplastic copolyetherester compositions having improved thermo-oxidation resistance ENICHEM SPA (IT) 1995-05-03 EP disclosed
US-5236979-A Containing synergistic mixture of tris/hydroxybenzyl/benzene and bis/alkylphenyl/pentaerythritol diphosphite ECP ENICHEM POLIMERI S.R.L. (IT) 1993-08-17 US disclosed
EP-0510545-A1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM S.p.A. (IT) 1992-10-28 EP disclosed
EP-0435346-A1 Elastomeric thermoplastic copolyetherester compositions having improved thermo-oxidation resistance ENICHEM S.p.A. (IT) 1991-07-03 EP disclosed
US-4123424-A Polymeric piperazinamides and membranes for reverse osmosis made therefrom MONTEDISON S.P.A. (IT) 1978-10-31 US disclosed