SCHEMBL9064154

SCHEMBL9064154

CCOC(=O)COc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.69
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
L3MBTL1 Q9Y468 3/20 0.61
ALDH1A1 P00352 4/20 0.59
MAPT P10636 3/20 0.59
KDM4E B2RXH2 1/20 0.59
TP53 P04637 1/20 0.59
HSD17B10 Q99714 1/20 0.59
GAA P10253 3/20 0.59
NPSR1 Q6W5P4 1/20 0.59
ELANE P08246 1/20 0.58
LMNA P02545 2/20 0.57
MAPK1 P28482 1/20 0.57
HTT P42858 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
RAB9A P51151 1/20 0.54
POLB P06746 1/20 0.53
PTPN1 P18031 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16035326 0.94 NPSR1 (0.66) HPGDMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL28688521 0.91 HPGD (0.61) HPGDMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL16090177 0.88 NPSR1 (0.59) HPGDMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL28447243 0.87 HPGD (0.58) HPGDMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL14594365 0.87 GAA (0.68) HPGDMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL377638 0.87 GAA (0.65) HPGDALDH1A1MAPTKDM4ETP53
SCHEMBL21991775 0.86 GAA (0.57) HPGDL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL3495434 0.85 PLA2G4B (0.68) HPGDALDH1A1MAPTKDM4ETP53
Bromide SCHEMBL1858718 0.85 GAA (0.63) HPGDALDH1A1MAPTKDM4ETP53
SCHEMBL9311487 0.85 TSHR (0.56) HPGDMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9719979-B2 Methods of identifying crosslinking molecules for polymers SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-01 US disclosed
US-20160290986-A1 METHODS OF IDENTIFYING CROSSLINKING MOLECULES FOR POLYMERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-10-06 US disclosed
EP-3068441-A1 METHODS OF IDENTIFYING CROSSLINKING MOLECULES FOR POLYMERS SABIC Global Technologies B.V. (NL) 2016-09-21 EP disclosed
WO-2015073847-A1 METHODS OF IDENTIFYING CROSSLINKING MOLECULES FOR POLYMERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-05-21 WO disclosed
US-7432268-B2 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases SCHERING CORPORATION (US) 2008-10-07 US disclosed
US-7432268-B2 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases SCHERING CORPORATION (US) 2008-10-07 US disclosed
EP-0625998-B1 RADIATION CROSSLINKED ELASTOMERS MINNESOTA MINING & MFG (US) 1996-06-05 EP disclosed
US-5407971-A Mixtures containing substituted benzophenones or acetophenones as crosslinking agents, for adhesives having bonding strength and shear strength MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US disclosed
EP-0625998-A1 RADIATION CROSSLINKED ELASTOMERS. MINNESOTA MINING & MFG (US) 1994-11-30 EP disclosed
WO-1993016131-A1 RADIATION CROSSLINKED ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-19 WO disclosed