Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823985 | 0.96 | — | — | |
| SCHEMBL1057516 | 0.96 | TSHR (0.50) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| SCHEMBL6269152 | 0.96 | — | — | |
| SCHEMBL22017 | 0.96 | — | — | |
| SCHEMBL8921614 | 0.96 | — | — | |
| Ethylene SCHEMBL460398 | 0.93 | TSHR (0.48) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| Acetone SCHEMBL11804126 | 0.93 | TSHR (0.48) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| Water SCHEMBL1080260 | 0.93 | TSHR (0.48) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| Phosphine SCHEMBL6536445 | 0.93 | TSHR (0.48) | TSHRTHRBALDH1A1CYP3A4TDP1 | |
| Charcoal, Activated SCHEMBL4931378 | 0.93 | TSHR (0.48) | TSHRTHRBALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482977-A | POLYMERS FOR EXTRUSION AND MOLDING | EASTMAN CHEMICAL COMPANY (US) | 1996-01-09 | — | — | US | disclosed |