Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45176 | 0.81 | HRH1 (0.55) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL30083973 | 0.81 | HRH1 (0.55) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL5360317 | 0.81 | SLC6A4 (0.58) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL872937 | 0.81 | HRH1 (0.55) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL5369650 | 0.79 | HRH1 (0.53) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL9063777 | 0.78 | HRH1 (0.56) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| Nitrogen SCHEMBL10825524 | 0.78 | HRH1 (0.51) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL9063780 | 0.78 | HRH1 (0.56) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL3334897 | 0.77 | HRH1 (0.64) | HRH1SLC6A4SLC6A2RIPK1LMNA | |
| SCHEMBL9064524 | 0.77 | HRH1 (0.54) | HRH1SLC6A4SLC6A2RIPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733364-A1 | MEDICINAL COMPOSITION FOR CIRCULATORY ORGAN | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |