Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855630 | 0.84 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL29901207 | 0.84 | BACE1 (0.53) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL29901056 | 0.84 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL14191577 | 0.84 | BACE1 (0.53) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL7448632 | 0.84 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL14355554 | 0.83 | BACE1 (0.50) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL1663438 | 0.82 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL30832846 | 0.82 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL5164310 | 0.82 | BACE1 (0.54) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL27544439 | 0.81 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | claimed |