⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020802 | 0.75 | — | — | |
| SCHEMBL4877351 | 0.72 | — | — | |
| SCHEMBL7786444 | 0.72 | — | — | |
| SCHEMBL31115 | 0.72 | — | — | |
| SCHEMBL8948 | 0.67 | — | — | |
| SCHEMBL5861030 | 0.67 | FFAR3 (0.40) | — | |
| SCHEMBL2723641 | 0.67 | — | — | |
| SCHEMBL1275690 | 0.67 | — | — | |
| SCHEMBL1425834 | 0.67 | — | — | |
| SCHEMBL8201994 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220744-A2 | SINGLE-STRANDED LOOP OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | WO | claimed |
| WO-2023152371-A1 | GUIDE OLIGONUCLEOTIDES FOR NUCLEIC ACID EDITING IN THE TREATMENT OF HYPERCHOLESTEROLEMIA | PROQR THERAPEUTICS II B.V. (NL) | 2023-08-17 | — | — | WO | claimed |
| US-20230257745-A1 | Circular siRNAs | BANK OF AMERICA, N.A. | 2023-08-17 | — | — | US | claimed |
| US-20230039928-A1 | Antisense oligonucleotides for nucleotide deamination in the treatment of Stargardt disease | PROQR THERAPEUTICS II B.V. (NL) | 2023-02-09 | — | — | US | claimed |
| WO-2022011214-A1 | CIRCULAR SIRNAS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-01-13 | — | — | WO | claimed |
| EP-3919619-A1 | MULTI-TARGETED SINGLE ENTITY CONJUGATES | Alnylam Pharmaceuticals, Inc. (US) | 2021-12-08 | — | — | EP | claimed |
| WO-2021130313-A1 | ANTISENSE OLIGONUCLEOTIDES FOR NUCLEOTIDE DEAMINATION IN THE TREATMENT OF STARGARDT DISEASE | PROQR THERAPEUTICS II B.V. (NL) | 2021-07-01 | — | — | WO | claimed |
| CN-110055057-B | Column [5] arene-based supramolecular polymer gel, and synthesis and application thereof | 西北师范大学 | 2021-03-23 | — | — | CN | claimed |
| EP-3324980-A1 | MULTI-TARGETED SINGLE ENTITY CONJUGATES | Alnylam Pharmaceuticals, Inc. (US) | 2018-05-30 | — | — | EP | claimed |
| WO-2017015109-A1 | MULTI-TARGETED SINGLE ENTITY CONJUGATES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-01-26 | — | — | WO | claimed |
| EP-0205005-B1 | NEW BIOLOGICALLY ACTIVE FLUORESCENT CYCLIC NUCLEOTIDES | UNIVERSITA' DEGLI STUDI DI PARMA (IT) | 1992-05-13 | — | — | EP | claimed |
| US-4748165-A | ANTISECRETORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-31 | — | — | US | claimed |
| EP-0248597-A2 | Phospholipase A2 inhibitors and methods of synthesis | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-12-09 | — | — | EP | claimed |
| EP-0060697-B1 | HETEROCYCLIC DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | claimed |
| EP-0205005-A2 | New biologically active fluorescent cyclic nucleotides | UNIVERSITA' DEGLI STUDI DI PARMA (IT) | 1986-12-17 | — | — | EP | claimed |
| EP-0067508-B1 | AMIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-10-30 | — | — | EP | claimed |
| EP-0067508-A1 | Amidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| EP-0060697-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | claimed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | claimed |