Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151795 | 1.00 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151186 | 0.91 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7231363 | 0.90 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151210 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8676818 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4632397 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151254 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4630778 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151276 | 0.87 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151643 | 0.87 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699191-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027979-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | IMMUNOPHARMACEUTICS, INC. (US) | 1994-12-08 | — | — | WO | disclosed |