Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | APEX1 | P27695 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 4/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065396 | 1.00 | POLB (0.44) | POLBL3MBTL1APEX1TDP1MAPT | |
| Hydrochloric Acid SCHEMBL9045263 | 0.99 | POLB (0.44) | POLBL3MBTL1APEX1TDP1MAPT | |
| SCHEMBL7843385 | 0.80 | MAPT (0.45) | POLBL3MBTL1APEX1TDP1MAPT | |
| SCHEMBL7843394 | 0.80 | MAPT (0.45) | POLBL3MBTL1APEX1TDP1MAPT | |
| SCHEMBL7828944 | 0.80 | POLB (0.41) | POLBL3MBTL1APEX1TDP1MAPT | |
| SCHEMBL7827587 | 0.80 | PDGFRB (0.38) | POLBL3MBTL1APEX1TDP1MAPT | |
| SCHEMBL1389017 | 0.80 | POLB (0.70) | POLBL3MBTL1APEX1TDP1MAPT | |
| SCHEMBL7825568 | 0.80 | POLB (0.70) | POLBL3MBTL1APEX1TDP1MAPT | |
| SCHEMBL1389018 | 0.80 | POLB (0.70) | POLBL3MBTL1APEX1TDP1MAPT | |
| Hydrochloric Acid SCHEMBL7823645 | 0.79 | PDGFRB (0.38) | POLBL3MBTL1APEX1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699185-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-03-06 | — | — | EP | claimed |