SCHEMBL9065706

SCHEMBL9065706

CCCOCCNCCN

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.48
CA6 P23280 5/20 0.48
CA7 P43166 5/20 0.48
CA9 Q16790 5/20 0.48
CA14 Q9ULX7 5/20 0.48
CA5B Q9Y2D0 5/20 0.48
RECQL P46063 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CA2 P00918 4/20 0.46
CA4 P22748 4/20 0.46
CA5A P35218 4/20 0.46
CA3 P07451 3/20 0.46
ALOX15 P16050 3/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CA1 P00915 2/20 0.46
TP53 P04637 1/20 0.46
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22905617 0.98 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL18852184 0.87 TSHR (0.38) CA12CA6CA7CA9CA14
SCHEMBL8015113 0.87 CA12 (0.62) CA12CA6CA7CA9CA14
SCHEMBL241373 0.87 TSHR (0.40) RECQLMEN1KMT2AALDH1A1LMNA
SCHEMBL17029282 0.86 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL5933429 0.85 TSHR (0.41) RECQLMEN1KMT2AALDH1A1LMNA
SCHEMBL5932918 0.85 TSHR (0.41) RECQLMEN1KMT2AALDH1A1KDM4E
SCHEMBL5932102 0.85 TSHR (0.43) RECQLMEN1KMT2AALDH1A1LMNA
SCHEMBL10959162 0.85 TSHR (0.43) RECQLMEN1KMT2AALDH1A1LMNA
SCHEMBL11414225 0.85 MEN1 (0.47) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed
EP-0449519-B1 Process for producing an impact copolymer SHELL OIL CO (US) 1996-05-08 EP disclosed
EP-0449519-A2 Process for producing an impact copolymer SHELL OIL COMPANY (US) 1991-10-02 EP disclosed