Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131575 | 0.98 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MAPK1TYR | |
| SCHEMBL29913934 | 0.98 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MAPK1TYR | |
| SCHEMBL9132587 | 0.98 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MAPK1TYR | |
| SCHEMBL9129475 | 0.95 | CYP3A4 (0.53) | CYP3A4TRPA1TDP1MAPK1TYR | |
| SCHEMBL5731786 | 0.89 | CYP3A4 (0.56) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL29620419 | 0.89 | CYP3A4 (0.55) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL29620420 | 0.89 | CYP3A4 (0.55) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL9318919 | 0.86 | CYP3A4 (0.46) | CYP3A4TRPA1TDP1MAPK1TYR | |
| SCHEMBL314237 | 0.83 | CYP3A4 (0.61) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL29376372 | 0.83 | CYP3A4 (0.61) | CYP3A4TRPA1TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523443-A | PROTECTIVE COATINGS | CASCHEM, INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0441416-B1 | Resin composition containing low-molecular weight compounds which form a polyester urethane hybrid network | DSM NV (NL) | 1995-12-06 | — | — | EP | disclosed |
| EP-0530302-B1 | COMPOSITION TO BE USED IN THE RESIN INJECTION MOULDING TECHNIQUE, CONTAINING LOW MOLECULAR WEIGHT COMPOUNDS JOINTLY FORMING A HYBRID NETWORK | DSM NV (NL) | 1995-11-15 | — | — | EP | disclosed |
| US-5426132-A | Alkoxysilyl-urethane acrylate with two curing mechanisms, one activated by exposure to ultraviolet radiation, second by exposure to moisture | CASCHEM, INC. (US) | 1995-06-20 | — | — | US | disclosed |
| US-5369176-A | Composition to be used in the resin injection molding technique, containing low molecular weight compounds jointly forming a hybrid network | DSM N.V. (NL) | 1994-11-29 | — | — | US | disclosed |
| US-5312943-A | Protective coatings | CASCHEM, INC. (US) | 1994-05-17 | — | — | US | disclosed |
| WO-1994009013-A1 | DUAL CURING CONFORMAL COATINGS | CASCHEM, INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| EP-0538923-A2 | Process for the preparation of a thermosetting elongated object | DSM N.V. (NL) | 1993-04-28 | — | — | EP | disclosed |
| EP-0530302-A1 | COMPOSITION TO BE USED IN THE RESIN INJECTION MOULDING TECHNIQUE, CONTAINING LOW MOLECULAR WEIGHT COMPOUNDS JOINTLY FORMING A HYBRID NETWORK. | DSM NV (NL) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991018033-A1 | COMPOSITION TO BE USED IN THE RESIN INJECTION MOULDING TECHNIQUE, CONTAINING LOW MOLECULAR WEIGHT COMPOUNDS JOINTLY FORMING A HYBRID NETWORK | DSM N.V. (NL) | 1991-11-28 | — | — | WO | disclosed |
| US-4824919-A | ENDCAPPED POLYETHERS, ACRYLATED RESINS; FLEXIBILITY, LIGHTWEIGHT, CHEMICAL RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
| US-4204010-A | Radiation curable, ethylenically unsaturated thixotropic agent and method of preparation | W. R. GRACE & CO. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4130213-A | OLEFIN-MALEIC ANHYDRIDE COPOLYMER, THIOL PLASTICIZER | W. R. GRACE & CO. (US) | 1978-12-19 | — | — | US | disclosed |
| US-4120721-A | ACRYLIC OR METHACRYLIC TERMINATED, URETHANE CONTAINING POLYENE; WATER INSOLUBLE VINYL MONOMER DILUENT; POLYTHIOL; PHOTOINITIATOR | W. R. GRACE & CO. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4112233-A | Hydantoin-containing polyene compositions | W. R. GRACE & CO. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4093098-A | COPOLYMER OF ALPHA-OLEFIN AND MALEIC ANHYDRIDE PLUS ISOCYANATE COPOLYMER | W. R. GRACE & CO. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4093097-A | COPOLYMER OF ALPHA-OLEFIN AND MALEIC ANHYDRIDE PLUS AN AMINE COPOLYMER | W. R. GRACE & CO. (US) | 1978-06-06 | — | — | US | disclosed |