SCHEMBL9065918

SCHEMBL9065918

C=C(C=C(C)C(=O)O)C(=O)OCCCC.CCC(=CC=Cc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
POLB P06746 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 6/20 0.40
LMNA P02545 4/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
GRIK1 P39086 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HPGD P15428 2/20 0.36
TSHR P16473 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12490541 0.92 KDM4E (0.57) KDM4EPOLBTDP1MEN1KMT2A
Oxirane SCHEMBL51272 0.87 KDM4E (0.53) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL11327799 0.87 KDM4E (0.52) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL1160270 0.84 TSHR (0.52) KDM4EPOLBTDP1MEN1KMT2A
Styrene SCHEMBL251772 0.82 KDM4E (0.45) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL4243868 0.82 KDM4E (0.60) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL9701897 0.81 KDM4E (0.45) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL8917316 0.81 KDM4E (0.45) KDM4EPOLBTDP1MEN1KMT2A
Styrene SCHEMBL4627611 0.80 KDM4E (0.43) KDM4EPOLBTDP1MEN1KMT2A
SCHEMBL10867479 0.79 KDM4E (0.45) KDM4EPOLBTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091255-A Bundles of elongated reinforcing nonconductive fibers AMERICAN CYANAMID COMPANY (US) 1992-02-25 US claimed
EP-0440970-A2 Molding granules, their manufacture and their use in the production of molded particles CYTEC TECHNOLOGY CORP. (US) 1991-08-14 EP claimed
EP-0440970-B1 Molding granules, their manufacture and their use in the production of molded articles CYTEC TECH CORP (US) 1996-09-11 EP disclosed
US-5091255-A Bundles of elongated reinforcing nonconductive fibers AMERICAN CYANAMID COMPANY (US) 1992-02-25 US disclosed
EP-0440970-A2 Molding granules, their manufacture and their use in the production of molded particles CYTEC TECHNOLOGY CORP. (US) 1991-08-14 EP disclosed