SCHEMBL9066214

CN1C(=O)CC[C@@]2(C)C1CC[C@@H]1[C@H]2CC[C@]2(C)C(N(C=O)C3CCCCC3)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	SRD5A1	P18405	16/20	1.00

▸	SRD5A2	P31213	4/20	0.72

▸	HSD17B7	P56937	2/20	0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9286015	0.95	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9065971	0.95	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9066669	0.84	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9270109	0.80	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9067243	0.80	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9066601	0.80	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9065996	0.79	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9286706	0.79	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9065998	0.79	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7
SCHEMBL9066263	0.78	SRD5A1 (1.00)	SRD5A1SRD5A2HSD17B7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5494914-A	USEFUL FOR TREATMENT OF DISEASES WHOSE PROGRESS IS AIDED BY ACTIVATION OF ANDROGEN RECEPTORS	ENDORECHERCHE (CA)	1996-02-27	—	—	US	disclosed
EP-0641211-A1	INHIBITORS OF TESTOSTERONE 5$g(a)-REDUCTASE ACTIVITY	ENDORECHERCHE INC. (CA)	1995-03-08	—	—	EP	disclosed
WO-1993023053-A1	INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY	ENDORECHERCHE INC. (CA)	1993-11-25	—	—	WO	disclosed