SCHEMBL9066473

SCHEMBL9066473

Cc1c(F)c(N2C[C@H]3C[C@@H](N)[C@H]3C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
KCNH2 Q12809 4/20 0.57
POLB P06746 2/20 0.57
CACNA1F O60840 1/20 0.57
MAPK1 P28482 1/20 0.57
CACNA1D Q01668 1/20 0.57
CACNA1S Q13698 1/20 0.57
CACNA1C Q13936 1/20 0.57
GSK3B P49841 8/20 0.49
TOP2A P11388 3/20 0.47
TOP2B Q02880 3/20 0.47
HRH3 Q9Y5N1 1/20 0.45
ALDH1A1 P00352 2/20 0.42
CHRM2 P08172 1/20 0.42
CHRM1 P11229 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9066469 1.00 MEN1 (0.58) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL9066480 1.00 MEN1 (0.58) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL7848648 0.93 MEN1 (0.54) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL9066506 0.93 MEN1 (0.54) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL9066510 0.93 MEN1 (0.54) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL9066836 0.91 CACNA1F (0.70) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL9066409 0.91 CACNA1F (0.70) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL9066831 0.91 CACNA1F (0.70) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL7841424 0.90 MEN1 (0.59) MEN1KMT2AKCNH2POLBCACNA1F
SCHEMBL7841431 0.90 MEN1 (0.59) MEN1KMT2AKCNH2POLBCACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527910-A BACTERICIDES; STAPHYLOCOCCUS, STREPTOCOCCUS INFECTIONS CHEIL FOODS & CHEMICALS, INC. (KR) 1996-06-18 US claimed
US-5527910-A BACTERICIDES; STAPHYLOCOCCUS, STREPTOCOCCUS INFECTIONS CHEIL FOODS & CHEMICALS, INC. (KR) 1996-06-18 US disclosed
EP-0677050-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES CHEIL FOODS & CHEMICALS, INC. (KR) 1995-10-18 EP disclosed
WO-1994015933-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES CHEIL FOODS & CHEMICALS, INC. (KR) 1994-07-21 WO disclosed