Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066426 | 1.00 | POLB (0.59) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL9066457 | 1.00 | POLB (0.59) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL9067998 | 1.00 | POLB (0.59) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL9066429 | 1.00 | POLB (0.59) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL11961790 | 0.91 | POLB (0.54) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL12975838 | 0.90 | POLB (0.57) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL12975835 | 0.90 | POLB (0.57) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL15398077 | 0.88 | POLB (0.49) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL11961787 | 0.88 | POLB (0.50) | POLBHTTAPEX1TDP1NPC1 | |
| SCHEMBL9453928 | 0.87 | HTT (0.52) | POLBHTTAPEX1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567349-A | Photo cross-linkable liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1996-10-22 | — | — | US | disclosed |