Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067651 | 1.00 | CYP2C9 (0.34) | CYP2C9SCN9AALDH1A1LMNAMAPT | |
| SCHEMBL9067385 | 0.92 | SCN9A (0.32) | SCN9AMEN1KMT2A | |
| SCHEMBL9067382 | 0.92 | SCN9A (0.32) | SCN9AMEN1KMT2A | |
| SCHEMBL9067146 | 0.85 | SCN9A (0.30) | SCN9A | |
| SCHEMBL9067152 | 0.85 | SCN9A (0.30) | SCN9A | |
| SCHEMBL9067622 | 0.82 | SCN9A (0.31) | SCN9A | |
| SCHEMBL9067616 | 0.82 | SCN9A (0.31) | SCN9A | |
| SCHEMBL9067358 | 0.81 | SCN9A (0.31) | SCN9A | |
| SCHEMBL9067363 | 0.81 | SCN9A (0.31) | SCN9A | |
| SCHEMBL8648095 | 0.81 | CYP2C9 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736513-A1 | 1-Fluorcyclohexene-difluorphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-10-09 | — | — | EP | disclosed |