⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685166 | 0.77 | — | — | |
| SCHEMBL18764259 | 0.75 | — | — | |
| SCHEMBL15942693 | 0.73 | — | — | |
| SCHEMBL22821869 | 0.73 | — | — | |
| SCHEMBL17248031 | 0.73 | — | — | |
| SCHEMBL22930952 | 0.73 | — | — | |
| SCHEMBL20159839 | 0.73 | — | — | |
| SCHEMBL19300237 | 0.73 | — | — | |
| SCHEMBL20060643 | 0.73 | — | — | |
| SCHEMBL22102502 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266127-A1 | METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES | ONL THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |
| EP-3233862-B1 | IMIDAZOPYRIDAZINE DERIVATIVES AS PI3KBETA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-07-03 | — | — | EP | disclosed |
| WO-2017120194-A1 | PYRIDINE AND PYRIDIMINE COMPOUNDS AS PI3K-GAMMA INHIBITORS | INCYTE CORPORATION (US) | 2017-07-13 | — | — | WO | disclosed |
| WO-2017060406-A1 | QUINOXALINE AND PYRIDOPYRAZINE DERIVATIVES AS PI3KBETA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-04-13 | — | — | WO | disclosed |
| EP-2748167-B1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-8188215-B2 | Metal-binding compounds and uses therefor | AMPIO PHARMACEUTICALS, INC. | 2012-05-29 | — | — | US | disclosed |