Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068467 | 0.90 | KDM4E (0.43) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL13160817 | 0.85 | KDM4E (0.39) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL11983517 | 0.85 | KDM4E (0.39) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL1648790 | 0.85 | KDM4E (0.39) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL9068491 | 0.84 | KDM4E (0.48) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL11983671 | 0.84 | TRPV1 (0.36) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL28395283 | 0.82 | KDM4E (0.37) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL9067541 | 0.82 | MAPK1 (0.47) | KDM4EMAPK1MAPTNPSR1ALDH1A1 | |
| SCHEMBL26607 | 0.81 | CA1 (0.41) | KDM4EMAPK1MAPTNPSR1TRPV1 | |
| SCHEMBL29349873 | 0.81 | CA1 (0.41) | KDM4EMAPK1MAPTNPSR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521237-A | HEAT, OXIDATION, AND RADIATION RESISTANT POLYOLEFINS FOR PROTECTIVE COATINGS THAT RESIST DISCOLORATION | CIBA-GEIGY CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |