Mecoprop

Mecoprop

SCHEMBL9068516

Cc1cc(Cl)ccc1O[C@H](C)C(=O)O.Cc1cc(Cl)ccc1O[C@H](C)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 1.00
HTR2A P28223 1/20 1.00
HTR2C P28335 1/20 1.00
HTR2B P41595 1/20 1.00
SMN1; SMN2 Q16637 5/20 0.62
LMNA P02545 4/20 0.62
MAPT P10636 3/20 0.62
ALOX12 P18054 1/20 0.62
HTT P42858 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
TRPM4 Q8TD43 1/20 0.61
PTGDR2 Q9Y5Y4 3/20 0.58
PTGDR Q13258 1/20 0.58
TDP1 Q9NUW8 3/20 0.51
KMT2A Q03164 2/20 0.51
ATM Q13315 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MAPK1 P28482 1/20 0.49
POLB P06746 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mecoprop SCHEMBL29426474 1.00 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop SCHEMBL7762943 1.00 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop-P SCHEMBL29817687 1.00 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop-P SCHEMBL572351 1.00 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop SCHEMBL54983 1.00 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop SCHEMBL53198 1.00 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop SCHEMBL11349605 1.00 TSHR (1.00) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop SCHEMBL1372900 0.98 TSHR (0.97) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop SCHEMBL3109901 0.98 TSHR (0.97) TSHRHTR2AHTR2CHTR2BSMN1; SMN2
Mecoprop SCHEMBL3101835 0.98 TSHR (0.97) TSHRHTR2AHTR2CHTR2BSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5529975-A CONTAINING WATER SOLUBLE ACRYLAMIDE POLYMER ALLIED COLLOIDS LIMITED (GB) 1996-06-25 US disclosed