Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 10/20 | 0.46 |
| ▸ | NPY1R | P25929 | 7/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 3/20 | 0.40 |
| ▸ | FNTB | P49356 | 3/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067431 | 0.95 | MME (0.44) | NPY4RNPY1RNPY5RMMENPY2R | |
| SCHEMBL10914543 | 0.89 | NPY4R (0.48) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL11333671 | 0.86 | MME (0.50) | NPY4RNPY1RNPY5RMMENPY2R | |
| SCHEMBL9068559 | 0.86 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2RFNTA | |
| SCHEMBL2867874 | 0.86 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL9068939 | 0.85 | NPY4R (0.43) | NPY4RNPY1RNPY5RMMENPY2R | |
| SCHEMBL11147609 | 0.85 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9450543 | 0.85 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29362097 | 0.85 | FNTA (0.47) | NPY4RNPY1RNPY5RNPY2RFNTA | |
| SCHEMBL9068523 | 0.85 | FNTA (0.45) | NPY4RNPY1RNPY5RNPY2RFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |