Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.72 |
| ▸ | ECE1 | P42892 | 12/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051310 | 0.90 | ACE (0.68) | ACEECE1 | |
| SCHEMBL11232284 | 0.89 | ACE (0.88) | ACEECE1 | |
| SCHEMBL11232292 | 0.89 | ACE (0.88) | ACEECE1 | |
| SCHEMBL11495529 | 0.88 | ACE (0.71) | ACEECE1 | |
| SCHEMBL11495534 | 0.88 | ACE (0.71) | ACEECE1 | |
| SCHEMBL25266213 | 0.87 | ACE (0.73) | ACEECE1 | |
| SCHEMBL25196442 | 0.87 | ACE (0.73) | ACEECE1 | |
| SCHEMBL30490366 | 0.87 | ACE (0.71) | ACEECE1 | |
| SCHEMBL8015180 | 0.87 | ECE1 (0.74) | ACEECE1 | |
| SCHEMBL30052301 | 0.86 | ACE (0.69) | ACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| US-4684660-A | Mercaptoacyldepeptides | E. R. SQUIBB & SONS, INC. (US) | 1987-08-04 | — | — | US | disclosed |