Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379335 | 1.00 | MME (0.70) | MMECYP1A2NPSR1NAALAD2FOLH1 | |
| SCHEMBL7387218 | 0.92 | MME (0.82) | MMEMMP2MMP9ADAMTS4ACE | |
| SCHEMBL23120319 | 0.91 | MME (0.60) | MMECYP1A2NPSR1NAALAD2MMP2 | |
| SCHEMBL7759675 | 0.91 | MME (0.60) | MMECYP1A2NPSR1NAALAD2MMP2 | |
| SCHEMBL7377188 | 0.89 | MME (0.69) | MMENPSR1NAALAD2ACECPA1 | |
| SCHEMBL5870198 | 0.89 | MME (0.88) | MMECYP1A2NPSR1NAALAD2MMP2 | |
| SCHEMBL5685972 | 0.89 | MME (0.59) | MMECYP1A2NPSR1NAALAD2MMP2 | |
| SCHEMBL8258027 | 0.89 | MME (0.88) | MMECYP1A2NPSR1NAALAD2MMP2 | |
| SCHEMBL3506385 | 0.88 | MME (0.58) | MMECYP1A2NPSR1NAALAD2FOLH1 | |
| SCHEMBL123574 | 0.88 | MME (0.58) | MMECYP1A2NPSR1NAALAD2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |