Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.62 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.57 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 12/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273193 | 0.87 | ACE (0.50) | FOLH1ACE | |
| SCHEMBL929013 | 0.86 | ACE (0.55) | ACE | |
| SCHEMBL929011 | 0.86 | ACE (0.55) | ACE | |
| SCHEMBL8726316 | 0.86 | ACE (0.55) | ACE | |
| SCHEMBL15828303 | 0.84 | NAALAD2 (0.58) | FOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL15847005 | 0.84 | NAALAD2 (0.63) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL15847003 | 0.84 | NAALAD2 (0.63) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL23835494 | 0.83 | ACE (0.71) | ACE | |
| SCHEMBL930664 | 0.83 | ACE (0.71) | ACE | |
| SCHEMBL7159495 | 0.83 | NAALAD2 (0.57) | FOLH1NAALAD2RIMKLAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |