⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962196 | 0.92 | — | — | |
| SCHEMBL31327306 | 0.81 | — | — | |
| SCHEMBL1931201 | 0.80 | — | — | |
| SCHEMBL12294516 | 0.77 | — | — | |
| SCHEMBL28428250 | 0.75 | MAPT (0.33) | — | |
| SCHEMBL21353932 | 0.73 | SIRT2 (0.35) | — | |
| SCHEMBL15629978 | 0.72 | — | — | |
| SCHEMBL6826055 | 0.72 | CYP2C19 (0.39) | — | |
| SCHEMBL38417 | 0.70 | — | — | |
| SCHEMBL28583320 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527476-A | RHODIUM CATALYST FOR CROSSLINKING METHYLHYDROGENSILOXANES IN TREATING FIBERS OR FABRICS | DOW CORNING CORPORATION (US) | 1996-06-18 | — | — | US | claimed |
| US-5464801-A | Crosslinking polysiloxanes | DOW CORNING CORPORATION (US) | 1995-11-07 | — | — | US | claimed |
| CN-109890831-A | Substituted nucleosides, nucleotide and their analog | 詹森生物制药有限公司 | 2019-06-14 | — | — | CN | disclosed |
| US-5527476-A | RHODIUM CATALYST FOR CROSSLINKING METHYLHYDROGENSILOXANES IN TREATING FIBERS OR FABRICS | DOW CORNING CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| US-5464801-A | Crosslinking polysiloxanes | DOW CORNING CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0661399-A1 | Catalyst compositions and methods for the preparation thereof | DOW CORNING CORPORATION (US) | 1995-07-05 | — | — | EP | disclosed |