Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069521 | 0.96 | P2RY2 (0.35) | P2RY12P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL4074082 | 0.82 | SLC28A1 (0.40) | P2RY12P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL5531485 | 0.82 | SLC28A1 (0.40) | P2RY12P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL4083526 | 0.82 | SLC28A1 (0.40) | P2RY12P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL4083099 | 0.82 | SLC28A1 (0.40) | P2RY12P2RY2P2RY4SLC28A1SLC28A2 | |
| SCHEMBL9069650 | 0.81 | PDE3A (0.40) | SLC29A1 | |
| SCHEMBL6223334 | 0.80 | P2RY12 (0.34) | P2RY12SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL5527658 | 0.79 | P2RY14 (0.34) | P2RY12 | |
| SCHEMBL9069639 | 0.77 | PDE3A (0.41) | SLC29A1 | |
| SCHEMBL3486287 | 0.76 | ENTPD2 (0.35) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583117-A | CARDIOVASCULAR, NERVOUS SYSTEM DISORDERS; DIABETES | PRO-NEURON, INC. (US) | 1996-12-10 | — | — | US | disclosed |