Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.54 |
| ▸ | ACP1 | P24666 | 8/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9069486 | 0.99 | ABCG2 (0.53) | ABCG2ACP1ABCB1ABCC1LMNA | |
| SCHEMBL9070426 | 0.85 | ACP1 (0.59) | ABCG2ACP1ABCB1MAPTTLR9 | |
| Hydrochloric Acid SCHEMBL9069913 | 0.84 | ABCG2 (0.54) | ABCG2ACP1ABCB1ABCC1MAPT | |
| Hydrochloric Acid SCHEMBL9073139 | 0.84 | ACP1 (0.58) | ABCG2ACP1ABCB1MAPTHPGD | |
| SCHEMBL9069455 | 0.80 | ACP1 (0.68) | ABCG2ACP1ABCB1 | |
| Hydrochloric Acid SCHEMBL9069972 | 0.79 | ACP1 (0.67) | ABCG2ACP1ABCB1LMNA | |
| Hydrochloric Acid SCHEMBL9073289 | 0.77 | ABCG2 (0.75) | ABCG2ACP1ABCB1LMNAMAPT | |
| SCHEMBL7623383 | 0.76 | EGFR (0.51) | EGFR | |
| SCHEMBL9070446 | 0.75 | ACP1 (0.50) | ABCG2ACP1ABCB1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL9069358 | 0.74 | ACP1 (0.49) | ABCG2ACP1ABCB1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506235-A | Quinoline derivatives as immunostimulants | PFIZER INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0597003-A1 | QUINOLINE DERIVATIVES AS IMMUNOSTIMULANTS | PFIZER INC. (US) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993003030-A1 | QUINOLINE DERIVATIVES AS IMMUNOSTIMULANTS | PFIZER INC. (US) | 1993-02-18 | — | — | WO | disclosed |