Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070965 | 0.94 | GCK (0.65) | GCKKCNH2RARGRARARARB | |
| SCHEMBL9070813 | 0.90 | GCK (0.55) | GCKKCNH2RARGRARARARB | |
| SCHEMBL9071025 | 0.86 | GCK (0.60) | GCKKCNH2RARGRARARARB | |
| SCHEMBL2667345 | 0.85 | GCK (0.58) | GCKKCNH2RARGRARARARB | |
| SCHEMBL2667475 | 0.84 | GCK (0.51) | GCKRARGRARARARB | |
| SCHEMBL9071015 | 0.84 | GCK (0.50) | GCKKCNH2 | |
| SCHEMBL2667355 | 0.82 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL2667480 | 0.82 | PRKAA2 (0.48) | GCKKCNH2RARGRARARARB | |
| SCHEMBL9071018 | 0.82 | GCK (0.49) | GCKKCNH2 | |
| SCHEMBL2667347 | 0.82 | GCK (0.54) | GCKKCNH2RARGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |