Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.59 |
| ▸ | GIPR | P48546 | 16/20 | 0.59 |
| ▸ | GLP1R | P43220 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | GCG | P01275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665430 | 0.93 | GCGR (0.60) | GCGRGIPRGLP1RKMT2ANPC1 | |
| SCHEMBL9071075 | 0.91 | GCGR (0.57) | GCGRGIPRGLP1RKMT2A | |
| SCHEMBL9070846 | 0.89 | GCGR (0.60) | GCGRGIPRGLP1RKMT2A | |
| SCHEMBL7100548 | 0.89 | GCGR (0.69) | GCGRGIPRGLP1RKMT2ANPC1 | |
| SCHEMBL7100544 | 0.89 | GCGR (0.69) | GCGRGIPRGLP1RKMT2ANPC1 | |
| SCHEMBL9070847 | 0.85 | GCGR (0.50) | GCGRGIPRGLP1R | |
| SCHEMBL2665387 | 0.84 | GCGR (0.78) | GCGRGIPRGLP1R | |
| SCHEMBL2665416 | 0.83 | GCGR (0.41) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2665453 | 0.82 | GCGR (0.57) | GCGRGIPRGLP1RKMT2ANPC1 | |
| SCHEMBL2665449 | 0.82 | GCGR (0.62) | GCGRGIPRGLP1RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051357-A1 | GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |