Sugi Predict

Sugi Predict / Compounds / SCHEMBL9070843

SCHEMBL9070843

SCHEMBL9070843

NC/N=C(/Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N(Cc1ccc(C(=O)NC[C@@H](O)C(=O)O)cc1)c1ccc(C2CCCCC2)cc1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GCGR P47871 20/20 0.69
▸ GIPR P48546 19/20 0.69
▸ GLP1R P43220 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665389 0.95 GCGR (0.66) GCGRGIPRGLP1R
SCHEMBL2652801 0.89 GCGR (0.86) GCGRGIPRGLP1R
SCHEMBL2652795 0.89 GCGR (0.86) GCGRGIPRGLP1R
SCHEMBL2665390 0.88 GCGR (0.60) GCGRGIPRGLP1R
SCHEMBL9071009 0.88 GCGR (0.66) GCGRGIPRGLP1R
SCHEMBL2665456 0.88 GCGR (0.65) GCGRGIPRGLP1R
SCHEMBL2665366 0.87 GCGR (0.74) GCGRGIPRGLP1R
SCHEMBL9070844 0.86 GCGR (0.73) GCGRGIPRGLP1R
SCHEMBL9071076 0.85 GCGR (0.76) GCGRGIPRGLP1R
SCHEMBL2653108 0.84 GCGR (0.81) GCGRGIPRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 — — WO disclosed