Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.60 |
| ▸ | GIPR | P48546 | 17/20 | 0.60 |
| ▸ | GLP1R | P43220 | 4/20 | 0.42 |
| ▸ | GCG | P01275 | 1/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070987 | 0.95 | GCGR (0.53) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663209 | 0.94 | GCGR (0.68) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2665451 | 0.89 | GCGR (0.56) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2665383 | 0.89 | GCGR (0.56) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2665413 | 0.89 | GCGR (0.55) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663371 | 0.88 | GCGR (0.61) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL13799988 | 0.88 | GCGR (0.53) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL9070983 | 0.86 | GCGR (0.51) | GCGRGIPRGCG | |
| SCHEMBL13800855 | 0.86 | GCGR (0.57) | GCGRGIPRGLP1RMGAT2 | |
| SCHEMBL4086686 | 0.85 | GCGR (0.57) | GCGRGIPRGLP1RGCGMGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051357-A1 | GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |