SCHEMBL9071002

SCHEMBL9071002

O=C(O)CCNC(=O)c1ccc(CN(/C(=N\CC(F)(F)F)Nc2cc(Cl)cc(Cl)c2)c2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.60
GIPR P48546 15/20 0.58
GLP1R P43220 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665384 0.92 GCGR (0.60) GCGRGIPRGLP1R
SCHEMBL2665392 0.90 GCGR (0.60) GCGRGIPRGLP1R
SCHEMBL2665424 0.89 GCGR (0.62) GCGRGIPRGLP1R
SCHEMBL2665379 0.89 GCGR (0.57) GCGRGIPRGLP1R
SCHEMBL9071076 0.88 GCGR (0.76) GCGRGIPRGLP1R
SCHEMBL9070961 0.87 GCGR (0.80) GCGRGIPRGLP1R
SCHEMBL2655049 0.86 GCGR (0.76) GCGRGIPRGLP1R
SCHEMBL2663193 0.86 GCGR (0.76) GCGRGIPRGLP1R
SCHEMBL9071005 0.85 GCGR (0.75) GCGRGIPRGLP1R
SCHEMBL2665390 0.84 GCGR (0.60) GCGRGIPRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed