Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MBTPS1 | Q14703 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241303 | 1.00 | KMT2A (0.43) | KMT2ACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL12828229 | 0.93 | KMT2A (0.44) | KMT2ACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL1238709 | 0.91 | CDK2 (0.39) | KMT2ACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL12204310 | 0.91 | CDK2 (0.39) | KMT2ACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL1241448 | 0.88 | CCNE1 (0.41) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL2668614 | 0.88 | CCNE1 (0.41) | KMT2ACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL1241353 | 0.88 | CCNE1 (0.41) | KMT2ACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL1240730 | 0.87 | CCNE1 (0.51) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL1240727 | 0.87 | CCNE1 (0.51) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL1241648 | 0.86 | KMT2A (0.44) | KMT2ACCNE2CCNE1CDK2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |