Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.49 |
| ▸ | GCG | P01275 | 4/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | GIPR | P48546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765203 | 0.76 | GCGR (0.54) | GCGRGCG | |
| SCHEMBL1765676 | 0.74 | GCGR (0.67) | GCGRGCG | |
| SCHEMBL12595380 | 0.74 | GCG (0.60) | GCGRGCG | |
| SCHEMBL1765322 | 0.74 | GCG (0.60) | GCGRGCG | |
| SCHEMBL13538749 | 0.74 | GCGR (0.64) | GCGRGCG | |
| SCHEMBL1765735 | 0.73 | GCGR (0.60) | GCGRGCG | |
| SCHEMBL1765319 | 0.73 | GCGR (0.62) | GCGRGCG | |
| SCHEMBL1765430 | 0.73 | GCGR (0.63) | GCGRGCG | |
| SCHEMBL1765678 | 0.72 | GCG (0.60) | GCGRGCG | |
| SCHEMBL1765585 | 0.71 | GCGR (0.64) | GCGRGCGGLP1RGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |