Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126115 | 0.90 | GCK (0.55) | GCK | |
| Hydrochloric Acid SCHEMBL3599905 | 0.89 | GCK (0.46) | GCKKDR | |
| Hydrochloric Acid SCHEMBL2660636 | 0.89 | GCK (0.54) | GCK | |
| SCHEMBL1330411 | 0.86 | GCK (0.54) | GCK | |
| Hydrochloric Acid SCHEMBL1330654 | 0.85 | GCK (0.53) | GCK | |
| Hydrochloric Acid SCHEMBL3600566 | 0.83 | GCK (0.44) | GCKKDR | |
| SCHEMBL1330522 | 0.81 | KDR (0.43) | GCKKDR | |
| Hydrochloric Acid SCHEMBL1328258 | 0.81 | KDR (0.42) | GCKKDR | |
| SCHEMBL3594350 | 0.79 | GCK (0.60) | GCKKDR | |
| SCHEMBL1329060 | 0.78 | GCK (0.64) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118718-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2008-10-02 | — | — | WO | disclosed |