SCHEMBL9071994

SCHEMBL9071994

CCCCCCC(Oc1ccc(OCc2ccc(C)cc2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 15/20 0.56
GCG P01275 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765383 0.94 GCGR (0.64) GCGRGCG
SCHEMBL1765811 0.93 GCGR (0.56) GCGRGCG
SCHEMBL1765787 0.92 GCGR (0.57) GCGRGCG
SCHEMBL1765362 0.92 GCGR (0.56) GCGRGCG
SCHEMBL1765622 0.92 GCGR (0.58) GCGRGCG
SCHEMBL1765543 0.92 GCGR (0.61) GCGRGCG
SCHEMBL1765705 0.91 GCGR (0.63) GCGRGCG
SCHEMBL1765698 0.91 GCGR (0.64) GCGRGCG
SCHEMBL1765533 0.91 GCGR (0.54) GCGRGCG
SCHEMBL1765382 0.91 GCGR (0.59) GCGRGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005123668-A1 GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2005-12-29 WO disclosed