Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCYAP1R1 | P41586 | 9/20 | 0.54 |
| ▸ | GCGR | P47871 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072183 | 0.91 | ADCYAP1R1 (0.55) | ADCYAP1R1GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2664434 | 0.89 | ADCYAP1R1 (0.59) | ADCYAP1R1GCGRCA1CA2CA9 | |
| SCHEMBL2664614 | 0.88 | ADCYAP1R1 (0.62) | ADCYAP1R1GCGR | |
| SCHEMBL9072258 | 0.87 | ADCYAP1R1 (0.54) | ADCYAP1R1GCGR | |
| SCHEMBL9072257 | 0.86 | ADCYAP1R1 (0.57) | ADCYAP1R1GCGRCA12CA1CA2 | |
| SCHEMBL9072181 | 0.85 | ADCYAP1R1 (0.55) | ADCYAP1R1GCGR | |
| SCHEMBL2664610 | 0.85 | NPC1 (0.56) | ADCYAP1R1GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2664423 | 0.85 | ADCYAP1R1 (0.52) | ADCYAP1R1GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2664431 | 0.82 | ADCYAP1R1 (0.54) | ADCYAP1R1GCGR | |
| SCHEMBL9072264 | 0.82 | ADCYAP1R1 (0.55) | ADCYAP1R1GCGRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |