Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 8/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466416 | 0.92 | TSHR (0.38) | TSHRTHRBSMPD1CES1GGPS1 | |
| SCHEMBL13517379 | 0.92 | TSHR (0.38) | TSHRTHRBSMPD1CES1GGPS1 | |
| SCHEMBL13517390 | 0.92 | TSHR (0.38) | TSHRTHRBSMPD1CES1GGPS1 | |
| SCHEMBL13518005 | 0.90 | TSHR (0.36) | TSHRTHRBSMPD1CES1GGPS1 | |
| SCHEMBL13517699 | 0.89 | TSHR (0.40) | SPHK2SPHK1TSHRTHRBSMPD1 | |
| SCHEMBL13517609 | 0.89 | TSHR (0.40) | SPHK2SPHK1TSHRTHRBSMPD1 | |
| SCHEMBL967960 | 0.89 | TSHR (0.40) | SPHK2SPHK1TSHRTHRBSMPD1 | |
| SCHEMBL13517509 | 0.89 | TSHR (0.33) | TSHRTHRBSMPD1CES1GGPS1 | |
| SCHEMBL13518015 | 0.88 | TSHR (0.35) | TSHRTHRBSMPD1CES1GGPS1 | |
| SCHEMBL13517112 | 0.87 | TSHR (0.38) | SPHK2SPHK1TSHRTHRBSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719800-A1 | Catalysts for the (co)polymerization of ethylene | Montell Technology Company bv (NL) | 1996-07-03 | — | — | EP | claimed |
| EP-0719800-A1 | Catalysts for the (co)polymerization of ethylene | Montell Technology Company bv (NL) | 1996-07-03 | — | — | EP | disclosed |