Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074726 | 1.00 | F2 (0.62) | F2PRSS1F10PLGPLAU | |
| SCHEMBL7346744 | 0.85 | F2 (0.54) | F2PRSS1F10PLG | |
| SCHEMBL9076763 | 0.83 | F2 (0.59) | F2PRSS1F10PLG | |
| SCHEMBL9076770 | 0.83 | F2 (0.59) | F2PRSS1F10PLG | |
| SCHEMBL9073567 | 0.83 | F2 (0.51) | F2PRSS1F10PLG | |
| SCHEMBL7339307 | 0.80 | F2 (0.56) | F2F10PLG | |
| SCHEMBL9077005 | 0.80 | F2 (0.49) | F2PRSS1F10PLGPLAU | |
| SCHEMBL9077003 | 0.80 | F2 (0.49) | F2PRSS1F10PLGPLAU | |
| SCHEMBL7338542 | 0.78 | F2 (0.54) | F2PRSS1F10PLG | |
| SCHEMBL9012346 | 0.78 | F2 (0.51) | F2PRSS1F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0623596-A1 | N-acylpyrrolidines or N-acylpiperidines having a guanidinyl- or amidinyl-substituted side chain as thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |