Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040363 | 0.90 | KDM4E (0.39) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13460519 | 0.77 | NPC1 (0.36) | — | |
| SCHEMBL29180621 | 0.77 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29180627 | 0.77 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3108247 | 0.77 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13328964 | 0.76 | GAA (0.35) | HTT | |
| SCHEMBL13328965 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL11141837 | 0.75 | HTT (0.41) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7935333 | 0.75 | EPHX2 (0.31) | — | |
| SCHEMBL25698444 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574162-A | CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES | CIBA-GEIGY CORPORATION (US) | 1996-11-12 | — | — | US | disclosed |
| US-5442071-A | Photostability | CIBA-GEIGY CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |