SCHEMBL9075843

SCHEMBL9075843

O=c1c(CCl)coc2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 9/20 0.71
▸ CYP11B1 P15538 3/20 0.58
▸ CYP11B2 P19099 3/20 0.58
▸ CYP17A1 P05093 1/20 0.58
▸ CYP19A1 P11511 1/20 0.58
▸ SIGMAR1 Q99720 2/20 0.57
▸ MAOA P21397 4/20 0.54
▸ PTPN1 P18031 1/20 0.51
▸ CA12 O43570 3/20 0.49
▸ CA1 P00915 3/20 0.49
▸ CA2 P00918 3/20 0.49
▸ CA9 Q16790 3/20 0.49
▸ HTR1A P08908 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ IL4I1 Q96RQ9 1/20 0.46
▸ FTO Q9C0B1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20378369 0.85 MAOB (0.76) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL6041859 0.84 MAOB (0.53) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL12655257 0.83 MAOB (0.73) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL6557580 0.83 MAOB (1.00) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL8359747 0.81 MAOB (0.71) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL292868 0.81 MAOB (0.71) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL2398512 0.79 CYP11B1 (0.77) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL293779 0.79 MAOB (0.67) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL29277424 0.79 MAOB (0.67) MAOBCYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL536553 0.79 MAOB (0.67) MAOBCYP11B1CYP11B2CYP17A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115636808-B Chromone-benzoyl hydrazone alpha-glucosidase inhibitor and preparation method and application thereof 贵州医科大学附属医院 2023-10-17 — — CN claimed
CN-115636808-A Chromone-benzoyl hydrazone alpha-glucosidase inhibitor as well as preparation method and application thereof 贵州医科大学附属医院 2023-01-24 — — CN claimed
EP-4747245-A1 PHARMACEUTICAL COMPOUNDS Almac Discovery Limited (GB) 2026-05-27 — — EP disclosed
US-12162863-B2 Modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2024-12-10 — — US disclosed
CN-115636808-B Chromone-benzoyl hydrazone alpha-glucosidase inhibitor and preparation method and application thereof 贵州医科大学附属医院 2023-10-17 — — CN disclosed
CN-115636808-A Chromone-benzoyl hydrazone alpha-glucosidase inhibitor as well as preparation method and application thereof 贵州医科大学附属医院 2023-01-24 — — CN disclosed
US-20220402898-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-12-22 — — US disclosed
US-20220402898-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-12-22 — — US disclosed
WO-2019238786-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2019-12-19 — — WO disclosed
US-5508417-A FUNGICIDES, BACTERICIDES, ALGICIDE ROHM AND HAAS COMPANY (US) 1996-04-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162863-B2 Modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS MAOB 730/4885CYP11B1 43/4885CYP11B2 50/4885
US-20220402898-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS MAOB 730/4885CYP11B1 43/4885CYP11B2 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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